Thoughts on Fiber Optics in Dissolution Testing

Practical Considerations When Using Fiber Optics for Dissolution Testing

Introduction The UV fiber optics system has emerged in dissolution testing of solid dosage forms as a useful alternative to conventional dissolution tests in both research & development and quality control. The system allows continuous in situ analysis of the drug concentration without the need for sample withdrawal and preparation. Therefore, this technique not only facilitates automation, but...

Fiber Optics

Dramatic improvements in the development of low-loss materials for optical fibers are responsible for the commercial viability of fiber-optic communications. Corning Incorporated pioneered the development and manufacture of ultra-low-loss glass fibers. C 0 R N I N G 272 Fundamentals of Photonics

Fiber Optics

Fiber Fourier optics.

The Fourier transform of a coherent optical image can be evaluated physically by use of a single lens plus free-space propagation, thereby providing the basis for the field of Fourier optics. I point out that one can similarly evaluate the discrete Fourier transform of a sampled or pixelated optical array physically by passing the discrete array amplitudes through a network of single-mode fiber...

Infrared Fiber Optics

Infrared (IR) optical fibers may be defined as fiber optics transmitting radiation with wavelengths greater than approximately 2 μm. The first IR fibers were fabricated in the mid-1960’s from chalcogenide glasses such as arsenic trisulfide with losses in excess of 10 dB/m. During the mid-1970’s, the interest in developing an efficient and reliable IR fiber for short-haul applications increased ...